Nonlinear Dynamics developers of bioinformatics software for proteomics and genomics research

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TotalLab|Progenesis













  TotalLab - Now Mac compatible
     
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TotalLab

 
     
 

Discover which of our solutions best meets your needs by identifying your area of work below:

Molecular Weight Calibration

The TL100 and TL120 versions both enable precise molecular weight determination of band material from a variety of 1D gels. TL120 contains tools which allow increased control over calibration for particularly distorted 1D gel images.

Quantitation and Normalisation of Band Material

The TL100 and TL120 software solutions both contain a complete range of tools to quantify band material and for the calculation of normalised band volumes. For in-depth quantitative studies, the advanced features in TL120 offer a higher degree of flexibility and facilitate accurate quantitation of bands on more problematic 1D gel images.

Lane Relationship Studies

The TL120 software has a powerful band matching facility which is flexible yet easy to use. There are tools available to visualise the results of matching and identify similarities within a single gel. When you have performed intra gel matching, lanes can be classified and identified.

When teamed with the DM database component, extensive comparisons and visualisation of band patterns across an entire research project are possible.

Data Archive and Mining

TL120 DM can store vast quantities of lane data which can be mined, queried and retrieved using the extensive array of tools available.

Summary of features in the TotalLab range:

Features in TotalLab TL100 TL120 TL120
DM
Automatic detection of lanes and bands
Automatic background subtraction
Lane templates
Image manipulation tools
Analysis protocols for batch processing  
Molecular weight calibration
Quantity calibration
Normalisation
Profile deconvolution
Rf calibration  
Band picking  
Band pattern matching - single gel  
Band pattern matching - lanes across multiple gels    
Band pattern queries    
Dendrogram - single gel  
Dendrogram - lanes from multiple gels    
Data archive and search facility    
Classification and identification tools    
Reports
 
     
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