Progenesis LC-MS - identify the real changes in your proteomics data...

Progenesis LC-MS is an expression analysis tool which utilises the advanced technology developed for the SameSpots approach. The SameSpots technology has revolutionised proteomics for 2D researchers - this technology has now been developed for application to LC-MS data offering researchers significant improvements in speed, objectivity and statistical power.

• Speed - Highly accurate alignment and a quality control step prepare data for fast optimal analysis, quickly producing reports on expression differences and peak lists for subsequent MS-MS.
• Objectivity - Automatic analysis of aligned images minimises the need for editing and the straightforward ‘visualise and validate’ view allows users to objectively select differences based on statistical significances.
• Statistical Power - 100% matching with no missing values increases the statistical power of experiments and paves the way for multivariate statistical analysis on complete data sets.

        

Workflow Overview:

Progenesis LC-MS can import and analyse LC-MS data in mz/XML format which is a standard data format.

Align Data
The trace data is aligned, utilising the unique and highly advanced alignment technology which has been developed for the SameSpots approach to 2D image analysis.

Analysis using the SameSpots approach
Fast and automatic analysis of trace data with matching across the complete data set.

Validate Hits
Review statistically ranked lists of data points using the range of visual tools provided. The streamlined workflow allows you to work logically through the data table and accept or reject areas for further study.

Statistical Analysis of Validated Hits – Explore the trends in your data based on the spots that you selected during validation using Progenesis Stats