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Progenesis QI

The next generation in LC-MS data analysis software.
Discover the significantly changing compounds in your samples.

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Progenesis QI is the new name for Progenesis CoMet

Progenesis QI software references

2016

Al Hamimi S, Heyman-Linden L, Plaza M, Turner C, Berger K, Spegel P (2016) Alterations in the plasma metabolite profile associated with improved hepatic function and glycemia in mice fed lingonberry supplemented high-fat diets. Mol Nutr Food Res (In press)

Ali MR, Wu Y, Han T, Zang X, Xiao H, Tang Y, Wu R, Fernandez FM, El-Sayed MA (2016) Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy. J Am Chem Soc 138:15434-15442

Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA (2016) Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol 23:678-688

Black C, Haughey SA, Chevallier OP, Galvin-King P, Elliott CT (2016) A comprehensive strategy to detect the fraudulent adulteration of herbs: The oregano approach. Food Chem 210:551-557

Blaise BJ, Correia G, Tin A, Young JH, Vergnaud AC, Lewis M, Pearce JT, Elliott P, Nicholson JK, Holmes E, Ebbels TM (2016) Power Analysis and Sample Size Determination in Metabolic Phenotyping. Anal Chem 88:5179-5188

Cao J, Li M, Chen J, Liu P, Li Z (2016) Effects of MeJA on Arabidopsis metabolome under endogenous JA deficiency. Sci Rep 6:37674

Carrizo D, Chevallier OP, Woodside JV, Brennan SF, Cantwell MM, Cuskelly G, Elliott CT (2016) Untargeted metabolomic analysis of human serum samples associated with exposure levels of Persistent organic pollutants indicate important perturbations in Sphingolipids and Glycerophospholipids levels. Chemosphere (In press)

Chen H, Cao G, Chen DQ, Wang M, Vaziri ND, Zhang ZH, Mao JR, Bai X, Zhao YY (2016) Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression. Redox Biol 10:168-178

Chen WW, Freinkman E, Wang T, Birsoy K, Sabatini DM (2016) Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism. Cell 166:1324-1337 e1311

Chen YX, Zhang XJ, Huang J, Zhou SJ, Liu F, Jiang LL, Chen M, Jian-Bo W, Yang DZ (2016) UHPLC/Q-TOFMS-based plasma metabolomics of polycystic ovary syndrome patients with and without insulin resistance. J Pharm Biomed Anal 121:141-150

Chen Z, Xu X, Zhang J, Liu Y, Li L, Wang W, Xu H, Jiang W, Wang Y (2016) Application of LC-MS-Based Global Metabolomic Profiling Methods to Human Mental Fatigue. Anal Chem 88:11293-11296

Chu H, Zhang A, Han Y, Lu S, Kong L, Han J, Liu Z, Sun H, Wang X (2016) Metabolomics approach to explore the effects of Kai-Xin-San on Alzheimer's disease using UPLC/ESI-Q-TOF mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 1015-1016:50-61

Cowan E, Kumar P, Burch KJ, Grieve DJ, Green BD, Graham SF (2016) Treatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics. Metabolomics 12:124

Dhungana S, Carlson JE, Pathmasiri W, McRitchie S, Davis M, Sumner S, Appt SE (2016) Impact of a western diet on the ovarian and serum metabolome. Maturitas 92:134-142

Fang H, Zhang A, Yu J, Wang L, Liu C, Zhou X, Sun H, Song Q, Wang X (2016) Insight into the metabolic mechanism of scoparone on biomarkers for inhibiting Yanghuang syndrome. Sci Rep 6:37519

Fluck M, Ruoss S, Mohl CB, Valdivieso P, Benn MC, von Rechenberg B, Laczko E, Hu J, Wieser K, Meyer DC, Gerber C (2016) Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep. J Steroid Biochem Mol Biol 165:382-395

Gray N, Adesina-Georgiadis K, Chekmeneva E, Plumb RS, Wilson ID, Nicholson JK (2016) Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies. Anal Chem 88:5742-5751

Huang W, Robert CA, Herve MR, Hu L, Bont Z, Erb M (2016) A mechanism for sequence specificity in plant-mediated interactions between herbivores. New Phytol (In press)

Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z (2016) A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med 22:421-426

Jones JW, Carter CL, Li F, Yu J, Pierzchalski K, Jackson IL, Vujaskovic Z, Kane MA (2016) Ultraperformance convergence chromatography-high resolution tandem mass spectrometry for lipid biomarker profiling and identification. Biomed Chromatogr (In press)

Kaakoush NO, Pickford R, Jaffe A, Ooi CY (2016) Is there a role for stool metabolomics in cystic fibrosis? Pediatr Int 58:808-811

Kim MS, Jin JS, Kwak YS, Hwang GS (2016) Metabolic Response of Strawberry (Fragaria x ananassa) Leaves Exposed to the Angular Leaf Spot Bacterium (Xanthomonas fragariae). J Agric Food Chem 64:1889-1898

Kim W, Peever TL, Park JJ, Park CM, Gang DR, Xian M, Davidson JA, Infantino A, Kaiser WJ, Chen W (2016) Use of metabolomics for the chemotaxonomy of legume-associated Ascochyta and allied genera. Sci Rep 6:20192

Kong Z, Li M, An J, Chen J, Bao Y, Francis F, Dai X (2016) The fungicide triadimefon affects beer flavor and composition by influencing Saccharomyces cerevisiae metabolism. Sci Rep 6:33552

Lai CJ, Zha L, Liu DH, Kang L, Ma X, Zhan ZL, Nan TG, Yang J, Li F, Yuan Y, Huang LQ (2016) Global profiling and rapid matching of natural products using diagnostic product ion network and in silico analogue database: Gastrodia elata as a case study. J Chromatogr A 1456:187-195

Laiakis EC, Pannkuk EL, Diaz-Rubio ME, Wang YW, Mak TD, Simbulan-Rosenthal CM, Brenner DJ, Fornace AJ, Jr. (2016) Implications of genotypic differences in the generation of a urinary metabolomics radiation signature. Mutat Res 788:41-49

Lesche D, Geyer R, Lienhard D, Nakas CT, Diserens G, Vermathen P, Leichtle AB (2016) Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. Metabolomics 12:159

Lewis MR, Pearce JT, Spagou K, Green M, Dona AC, Yuen AH, David M, Berry DJ, Chappell K, Horneffer-van der Sluis V, Shaw R, Lovestone S, Elliott P, Shockcor J, Lindon JC, Cloarec O, Takats Z, Holmes E, Nicholson JK (2016) Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping. Anal Chem 88:9004-9013

McIlroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegovic M, Whitfield PD, Mody N (2016) Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol 100:86-97

Mnich E, Vanholme R, Oyarce P, Liu S, Lu F, Goeminne G, Jorgensen B, Motawie MS, Boerjan W, Ralph J, Ulvskov P, Moller BL, Bjarnholt N, Harholt J (2016) Degradation of lignin beta-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6. Plant Biotechnol J (In press)

Nakabayashi R, Sawada Y, Aoyagi M, Yamada Y, Hirai MY, Sakurai T, Kamoi T, Rowan DD, Saito K (2016) Chemical Assignment of Structural Isomers of Sulfur-Containing Metabolites in Garlic by Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry. J Nutr 146:397S-402S

Paglia G, Stocchero M, Cacciatore S, Lai S, Angel P, Alam MT, Keller M, Ralser M, Astarita G (2016) Unbiased Metabolomic Investigation of Alzheimer's Disease Brain Points to Dysregulation of Mitochondrial Aspartate Metabolism. J Proteome Res 15:608-618

Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E (2016) Revealing disease-associated pathways by network integration of untargeted metabolomics. Nat Methods 13:770-776

Plucinska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield PD, Doherty MK, Mingarelli M, Welch A, Riedel G, Delibegovic M, Platt B (2016) Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia 59:1513-1523

Prudent M, Stauber F, Rapin A, Hallen S, Pham N, Abonnenc M, Marvin L, Rochat B, Tissot JD, Lion N (2016) Small-Scale Perfusion Bioreactor of Red Blood Cells for Dynamic Studies of Cellular Pathways: Proof-of-Concept. Front Mol Biosci 3:11

Rusilowicz M, Dickinson M, Charlton A, O'Keefe S, Wilson J (2016) A batch correction method for liquid chromatography-mass spectrometry data that does not depend on quality control samples. Metabolomics 12:56

Saigusa D, Okamura Y, Motoike IN, Katoh Y, Kurosawa Y, Saijyo R, Koshiba S, Yasuda J, Motohashi H, Sugawara J, Tanabe O, Kinoshita K, Yamamoto M (2016) Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery. PLoS One 11:e0160555

Salem MA, Juppner J, Bajdzienko K, Giavalisco P (2016) Protocol: a fast, comprehensive and reproducible one-step extraction method for the rapid preparation of polar and semi-polar metabolites, lipids, proteins, starch and cell wall polymers from a single sample. Plant Methods 12:45

Schmidt R, Ostorhazi E, Wende E, Knappe D, Hoffmann R (2016) Pharmacokinetics and in vivo efficacy of optimized oncocin derivatives. J Antimicrob Chemother 71:1003-1011

Shahaf N, Rogachev I, Heinig U, Meir S, Malitsky S, Battat M, Wyner H, Zheng S, Wehrens R, Aharoni A (2016) The WEIZMASS spectral library for high-confidence metabolite identification. Nat Commun 7:12423

Shen S, Weng R, Li L, Xu X, Bai Y, Liu H (2016) Metabolomic Analysis of Mouse Embryonic Fibroblast Cells in Response to Autophagy Induced by Acute Starvation. Sci Rep 6:34075

Shi H, Hu L, Chen S, Bao W, Yang S, Zhao X, Sun C (2016) Metabolomics analysis of urine from rats administered with long-term, low-dose acrylamide by ultra-performance liquid chromatography-mass spectrometry. Xenobiotica:1-11

Steenackers W, Cesarino I, Klima P, Quareshy M, Vanholme R, Corneillie S, Kumpf RP, Van de Wouwer D, Ljung K, Goeminne G, Novak O, Zazimalova E, Napier R, Boerjan W, Vanholme B (2016) The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis. Plant Physiol 172:874-888

Vaughan D, Brogioli M, Maier T, White A, Waldron S, Rittweger J, Toigo M, Wettstein J, Laczko E, Fluck M (2016) The Angiotensin Converting Enzyme Insertion/Deletion Polymorphism Modifies Exercise-Induced Muscle Metabolism. PLoS One 11:e0149046

Wali S, Gupta R, Yu JJ, Mfuh A, Gao X, Guentzel MN, Chambers JP, Abu Bakar S, Zhong G, Arulanandam BP (2016) Guinea pig genital tract lipidome reveals in vivo and in vitro regulation of phosphatidylcholine 16:0/18:1 and contribution to Chlamydia trachomatis serovar D infectivity. Metabolomics 12 (In press)

Walton A, Stes E, Goeminne G, Braem L, Vuylsteke M, Matthys C, De Cuyper C, Staes A, Vandenbussche J, Boyer FD, Vanholme R, Fromentin J, Boerjan W, Gevaert K, Goormachtig S (2016) The Response of the Root Proteome to the Synthetic Strigolactone GR24 in Arabidopsis. Mol Cell Proteomics 15:2744-2755

Wang J, Qi P, Hou J, Shen Y, Yang M, Bi Q, Deng Y, Shi X, Feng R, Feng Z, Wu W, Guo D (2016) The profiling of the metabolites of hirsutine in rat by ultra-high performance liquid chromatography coupled with linear ion trap Orbitrap mass spectrometry: An improved strategy for the systematic screening and identification of metabolites in multi-samples in vivo. J Pharm Biomed Anal 134:149-157

Yang Z, Hou JJ, Qi P, Yang M, Yan BP, Bi QR, Feng RH, Yang WZ, Wu WY, Guo DA (2016) Colon-derived uremic biomarkers induced by the acute toxicity of Kansui radix: A metabolomics study of rat plasma and intestinal contents by UPLC-QTOF-MS(E). J Chromatogr B Analyt Technol Biomed Life Sci 1026:193-203

Yao C, Yang W, Zhang J, Qiu S, Chen M, Shi X, Pan H, Wu W, Guo D (2016) UHPLC-Q-TOF-MS-based metabolomics approach to compare the saponin compositions of Xueshuantong Injection and Xuesaitong Injection. J Sep Sci (In press)

Zhang A, Liu Q, Zhao H, Zhou X, Sun H, Nan Y, Zou S, Ma CW, Wang X (2016) Phenotypic characterization of nanshi oral liquid alters metabolic signatures during disease prevention. Sci Rep 6:19333

Zhang J, Yang W, Li S, Yao S, Qi P, Yang Z, Feng Z, Hou J, Cai L, Yang M, Wu W, Guo DA (2016) An intelligentized strategy for endogenous small molecules characterization and quality evaluation of earthworm from two geographic origins by ultra-high performance HILIC/QTOF MS(E) and Progenesis QI. Anal Bioanal Chem 408:3881-3890


2015

Ashraf-Khorassani M, Yang J, Rainville P, Jones MD, Fountain KJ, Isaac G, Taylor LT (2015) Ultrahigh performance supercritical fluid chromatography of lipophilic compounds with application to synthetic and commercial biodiesel. J Chromatogr B Analyt Technol Biomed Life Sci 983-984:94-100

Avin-Wittenberg T, Bajdzienko K, Wittenberg G, Alseekh S, Tohge T, Bock R, Giavalisco P, Fernie AR (2015) Global Analysis of the Role of Autophagy in Cellular Metabolism and Energy Homeostasis in Arabidopsis Seedlings under Carbon Starvation. Plant Cell 27:306-322

Boulard C, Bardet M, Chardot T, Dubreucq B, Gromova M, Guillermo A, Miquel M, Nesi N, Yen-Nicolay S, Jolivet P (2015) The structural organization of seed oil bodies could explain the contrasted oil extractability observed in two rapeseed genotypes. Planta 242:53-68

Burch TC, Isaac G, Booher CL, Rhim JS, Rainville P, Langridge J, Baker A, Nyalwidhe JO (2015) Comparative Metabolomic and Lipidomic Analysis of Phenotype Stratified Prostate Cells. PLoS One 10:e0134206

Chetwynd AJ, Abdul-Sada A, Holt SG, Hill EM (2015) Use of a pre-analysis osmolality normalisation method to correct for variable urine concentrations and for improved metabolomic analyses. J Chromatogr A (In press)

Chevallier OP, Graham SF, Alonso E, Duffy C, Silke J, Campbell K, Botana LM, Elliott CT (2015) New insights into the causes of human illness due to consumption of azaspiracid contaminated shellfish. Sci Rep 5:9818

Dai W, Qi D, Yang T, Lv H, Guo L, Zhang Y, Zhu Y, Peng Q, Xie D, Tan J, Lin Z (2015) Nontargeted Analysis Using Ultraperformance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry Uncovers the Effects of Harvest Season on the Metabolites and Taste Quality of Tea (Camellia sinensis L.). J Agric Food Chem 63:9869-9878

Deutsch EW, Mendoza L, Shteynberg D, Slagel J, Sun Z, Moritz RL (2015) Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics. Proteomics Clin Appl 9:745-754 (in press)

Graham SF, Chevallier OP, Elliott CT, Holscher C, Johnston J, McGuinness B, Kehoe PG, Passmore AP, Green BD (2015) Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease. PLoS One 10:e0119452

Gray N, Lewis MR, Plumb RS, Wilson ID, Nicholson JK (2015) High-Throughput Microbore UPLC-MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies. J Proteome Res 14:2714-2721

Haoula Z, Ravipati S, Stekel DJ, Ortori CA, Hodgman C, Daykin C, Raine-Fenning N, Barrett DA, Atiomo W (2015) Lipidomic analysis of plasma samples from women with polycystic ovary syndrome. Metabolomics 11:657-666

Holcapek M, Cervena B, Cifkova E, Lisa M, Chagovets V, Vostalova J, Bancirova M, Galuszka J, Hill M (2015) Lipidomic analysis of plasma, erythrocytes and lipoprotein fractions of cardiovascular disease patients using UHPLC/MS, MALDI-MS and multivariate data analysis. J Chromatogr B Analyt Technol Biomed Life Sci 990:52-63

Kim D, Fiske BP, Birsoy K, Freinkman E, Kami K, Possemato RL, Chudnovsky Y, Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M, Ramkissoon SH, Ligon KL, Kang SW, Snuderl M, Vander Heiden MG, Sabatini DM (2015) SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature 520:363-367

Lin L, Lin H, Zhang M, Ni B, Yin X, Qu C, Ni J (2015) A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. J Hazard Mater 299:249-259

Liu F, Bai X, Ding RB, Hu YJ, Su H, Wan JB (2015) UPLC/Q-TOFMS-Based Metabolomics Studies on the Protective Effect of Panax notoginseng Saponins on Alcoholic Liver Injury. Am J Chin Med 43:695-714

Liu H, Zhang L, Zhao B, Zhang Z, Qin L, Zhang Q, Wang Q, Lu Z, Gao X (2015) Hypothalamus metabolomic profiling to elucidate the tissue-targeted biochemical basis of febrile response in yeast-induced pyrexia rats. Chem Biol Interact 231:61-70

Maldini M, Natella F, Baima S, Morelli G, Scaccini C, Langridge J, Astarita G (2015) Untargeted Metabolomics Reveals Predominant Alterations in Lipid Metabolism Following Light Exposure in Broccoli Sprouts. Int J Mol Sci 16:13678-13691

McIlroy GD, Tammireddy SR, Maskrey BH, Grant L, Doherty MK, Watson DG, Delibegovic M, Whitfield PD, Mody N (2015) Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue. Biochem Pharmacol (In press)

Mertens J, Pollier J, Vanden Bossche R, Lopez-Vidriero I, Franco-Zorrilla JM, Goossens A (2015) The bHLH Transcription Factors TSAR1 and TSAR2 Regulate Triterpene Saponin Biosynthesis in Medicago truncatula. Plant Physiol 170:194-210

Milner JJ, Rebeles J, Dhungana S, Stewart DA, Sumner SC, Meyers MH, Mancuso P, Beck MA (2015) Obesity Increases Mortality and Modulates the Lung Metabolome during Pandemic H1N1 Influenza Virus Infection in Mice. J Immunol 194:4846-4859

Mulek M, Fekete A, Wiest J, Holzgrabe U, Mueller MJ, Hogger P (2015) Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach. J Pharm Biomed Anal 114:71-81

Nakabayashi R, Yang Z, Nishizawa T, Mori T, Saito K (2015) Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis. J Nat Prod 78:1179-1183

Neubauer C, Dalleska NF, Cowley ES, Shikuma NJ, Wu CH, Sessions AL, Newman DK (2015) Lipid remodeling in Rhodopseudomonas palustris TIE-1 upon loss of hopanoids and hopanoid methylation. Geobiology 13:443-453

Pacini T, Fu W, Gudmundsson S, Chiaravalle AE, Brynjolfson S, Palsson BO, Astarita G, Paglia G (2015) Multidimensional analytical approach based on UHPLC-UV-ion mobility-MS for the screening of natural pigments. Anal Chem 87:2593-2599

Passos-Castilho AM, Carvalho VM, Cardozo KH, Kikuchi L, Chagas AL, Gomes-Gouvea MS, Malta F, de Seixas-Santos Nastri AC, Pinho JR, Carrilho FJ, Granato CF (2015) Serum lipidomic profiling as a useful tool for screening potential biomarkers of hepatitis B-related hepatocellular carcinoma by ultraperformance liquid chromatography-mass spectrometry. BMC Cancer 15:985

Stark TD, Losch S, Wakamatsu J, Balemba OB, Frank O, Hofmann T (2015) UPLC-ESI-TOF MS-Based Metabolite Profiling of the Antioxidative Food Supplement Garcinia buchananii. J Agric Food Chem 63:7169-7179

Stewart CJ, Nelson A, Treumann A, Skeath T, Cummings SP, Embleton ND, Berrington JE (2015) Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis. Pediatr Res (In press)

Tonoli D, Furstenberger C, Boccard J, Hochstrasser D, Jeanneret F, Odermatt A, Rudaz S (2015) Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells. Chem Res Toxicol 28:955-966

Wang_XK (2015) Identification of particulate organosulfates in three megacities at the middle and lower reaches of the Yangtze River. Atmos Chem Phys Discuss 15:21415–21448

Watschinger K, Keller MA, McNeill E, Alam MT, Lai S, Sailer S, Rauch V, Patel J, Hermetter A, Golderer G, Geley S, Werner-Felmayer G, Plumb RS, Astarita G, Ralser M, Channon KM, Werner ER (2015) Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome. Proc Natl Acad Sci U S A 112:2431-2436

Yang Z, Hou JJ, Qi P, Yang M, Yan BP, Bi QR, Feng RH, Yang WZ, Wu WY, Guo DA (2015) Colon-derived uremic biomarkers induced by the acute toxicity of Kansui radix: A metabolomics study of rat plasma and intestinal contents by UPLC-QTOF-MS. J Chromatogr B Analyt Technol Biomed Life Sci (in press)

Zhang ZH, Wei F, Vaziri ND, Cheng XL, Bai X, Lin RC, Zhao YY (2015) Metabolomics insights into chronic kidney disease and modulatory effect of rhubarb against tubulointerstitial fibrosis. Sci Rep 5:14472

Zhao YY, Wang HL, Cheng XL, Wei F, Bai X, Lin RC, Vaziri ND (2015) Metabolomics analysis reveals the association between lipid abnormalities and oxidative stress, inflammation, fibrosis, and Nrf2 dysfunction in aristolochic acid-induced nephropathy. Sci Rep 5:12936

Zhao Y, Liu T, Luo J, Zhang Q, Xu S, Han C, Xu J, Chen M, Chen Y, Kong L (2015) Integration of a Decrescent Transcriptome and Metabolomics Dataset of Peucedanum praeruptorum to Investigate the CYP450 and MDR Genes Involved in Coumarins Biosynthesis and Transport. Front Plant Sci 6:996

Zhou T, Wang M, Cheng H, Cui C, Su S, Xu P, Xue M (2015) UPLC-HRMS based metabolomics reveals the sphingolipids with long fatty chains and olefinic bonds up-regulated in metabolic pathway for hypoxia preconditioning. Chem Biol Interact 242:145-152


2014

Astarita G, McKenzie JH, Wang B, Strassburg K, Doneanu A, Johnson J, Baker A, Hankemeier T, Murphy J, Vreeken RJ, Langridge J, Kang JX (2014) A protective lipidomic biosignature associated with a balanced omega-6/omega-3 ratio in fat-1 transgenic mice. PLoS One 9:e96221

Avanesov AS, Ma S, Pierce KA, Yim SH, Lee BC, Clish CB, Gladyshev VN (2014) Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation. Elife 3:e02077

Damen CW, Isaac G, Langridge J, Hankemeier T, Vreeken RJ (2014) Enhanced lipid isomer separation in human plasma using reversed-phase UPLC with ion-mobility/high-resolution MS detection. J Lipid Res 55:1772-1783

Laiakis EC, Strassburg K, Bogumil R, Lai S, Vreeken RJ, Hankemeier T, Langridge J, Plumb RS, Fornace AJ, Jr., Astarita G (2014) Metabolic phenotyping reveals a lipid mediator response to ionizing radiation. J Proteome Res 13:4143-4154

Paglia G, Angel PM, Williams JP, Richardson K, Olivos HJ, Thompson JW, Menikarachchi LC, Lai S, Walsh C, Moseley MA, Plumb RS, Grant DF, Palsson BO, Langridge JI, Geromanos SJ, Astarita G (2014) Ion-Mobility-Derived Collision Cross Section as an Additional Measure for Lipid Fingerprinting and Identification. Anal Chem

Paglia G, Williams JP, Menikarachchi L, Thompson JW, Tyldesley-Worster R, Halldorsson S, Rolfsson O, Moseley A, Grant D, Langridge J, Palsson BO, Astarita G (2014) Ion mobility derived collision cross sections to support metabolomics applications. Anal Chem 86:3985-3993

Sedic M, Gethings LA, Vissers JP, Shockcor JP, McDonald S, Vasieva O, Lemac M, Langridge JI, Batinic D, Pavelic SK (2014) Label-free mass spectrometric profiling of urinary proteins and metabolites from paediatric idiopathic nephrotic syndrome. Biochem Biophys Res Commun 452:21-26

Sundin L, Vanholme R, Geerinck J, Goeminne G, Hofer R, Kim H, Ralph J, Boerjan W (2014) Mutation of the Inducible ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE2 Alters Lignin Composition and Improves Saccharification. Plant Physiol 166:1956-1971

Van Acker R, Leple JC, Aerts D, Storme V, Goeminne G, Ivens B, Legee F, Lapierre C, Piens K, Van Montagu MC, Santoro N, Foster CE, Ralph J, Soetaert W, Pilate G, Boerjan W (2014) Improved saccharification and ethanol yield from field-grown transgenic poplar deficient in cinnamoyl-CoA reductase. Proc Natl Acad Sci U S A 111:845-850

Zhang A, Zhou X, Zhao H, Guan Y, Zhou S, Yan GL, Ma Z, Liu Q, Wang X (2014) Rapidly improved determination of metabolites from biological data sets using the high-efficient TransOmics tool. Mol Biosyst 10:2160-2165